Reporting from the scene ToLOnews journalist Gulabuddin Ghubar said he saw at least 20 ambulances racing away from the scene taking the wounded to hospital.
Public healthy ministry spokesperson Mohammad Ismayeel Kawosi confirmed the numbers, the channel reported.
The latest attack will add pressure on President Ashraf Ghani and his USA allies, who have expressed growing confidence that a new more aggressive military strategy has succeeded in driving Taliban insurgents back from major provincial centres.
Hassina Safi, a member of High Peace Council, which is charged with negotiating with the Taliban, told AFP: "It targeted our checkpoint".
Thick, dark smoke could be seen rising from the site of the explosion near the old Interior Ministry building.
The Jamuriate hospital, the nearest to the scene, was overwhelmed, with many people lying in corridors waiting to be treated. The force of the blast shattered windows of surrounding buildings while causing few low-rise structures to collapse.
Outside, civilians walked through debris-covered streets carrying wounded people on their backs as paramedics loaded several bodies at a time into ambulances to take them to medical facilities around the city. There were dozens of people who were killed and wounded.
The blast comes just days after 22 people were killed during a 17-hour siege of Kabul's Intercontinental Hotel and the offices of Save The Children in the eastern city of Jalalabad were attacked.
The explosion ripped through Kabul shortly before 1pm on Saturday afternoon and shook building kilometers away.
India on Saturday strongly condemned the "barbaric and dastardly" terrorist attack in Kabul on the same day.
This quake was measured a 7.9 magnitude on the Richter magnitude scale. "I figured I'd probably just better play it safe". Residents along B.C.'s coast were woken up in the middle of the night by warning sirens shortly after the quake hit.
Obviously this is the attitude we need to show in the next game [at home to Brighton and Hove Albion] - it's massive for us. Mauricio Pochettino confirmed as much after the match, stating: "Players were affected last week but that's no excuse".
Irrespective of whether you are playing at home or outside. "In these conditions, you will get out playing too many shots". Meanwhile, Indian captain Virat Kohli believes his side is still the best in the world when it comes to Test cricket.
Southampton are winless in 10 league games are a point and a place above the relegation zone while Tottenham are fifth. Things get underway at the traditional 3pm. "Unfortunately I can't give you any update or opinion on that".
Investigators went to the house and freed the children, prompting days of investigations that led to a series of charges Thursday. But, ultimately, whatever happens to Louise and David Turpin, their children must somehow move on and carry on with their lives.
Because now he is now saying 'never mind, I didn't mean it, ' and is himself calling for an even shorter, short-term funding bill. All national security and military personnel deemed "essential" would continue to report to work, but they wouldn't get paid .
England all-rounder Ben Stokes is "raring to go" after being made available for selection again, says head coach Trevor Bayliss. The suspension on Stokes was lifted following the England and Wales Cricket Board ( ECB ) meeting on Wednesday.
Before that, Zafar was a content vice president at Barnes & Noble's Nook e-reader division, according to his LinkedIn profile . Department of Justice fined the company $450 million as part of an antitrust lawsuit that involved five major publishers.
Marshall County High had 1,300 students in the 2014-2015 school year, according to the National Center for Education Statistics. There have been 13 school shootings - in California, Texas, Ohio, Illinois, Washington state and New Mexico - this year.
Nine of the 12 members said Zinke hadn't heard out their agenda for the parks service, which oversees national historic sites. The board was established in 1935 and is required to meet twice each year, though that has yet to happen under Trump .
Intel lifts S&P, Dow to new highs; Starbucks weighs on Nasdaq
In the energy market, oil prices settled higher, with crude also posting a weekly gain as the weaker dollar underpinned prices. As a result, the yield on the benchmark ten-year note, which moves opposite of its price, fell by 3.3 basis points to 2.621%.
MSU president resigns following Nassar sentencing
Former Spartan athletes are among the more than 150 women and girls who have spoken over the last week at Nassar's sentencing . The police recommended criminal charges against Nassar, but the Ingham County Prosecutor's Office dismissed the case.
Major payments firm to stop accepting bitcoin
On Tuesday, however, product manager Tom Karlo announced that the company will be winding down support for bitcoin payments. We may also think of steller if its use continues to grow while Bitcoin Cash and light coin would also be highly considered.
Microsoft unveils $200 Windows 10 laptops for schools
Microsoft also announced two analogous systems (at the same USA prices) from JP, its big partner in emerging economies. The company will roll out a new Chemistry update for Minecraft: Education Edition this spring.
Gunmen storm Kabul luxury hotel
The siege lasted almost 14 hours, during whichsix assailants either blew themselves up or were gunned down by Afghan forces. The attack was claimed by the Taliban , seeking to re-impose Islamic rule and drive worldwide forces out of Afghanistan .
SF Meeting Set To Confirm McDonald As Next Party Leader
This morning Mary Lou McDonald officially became the next President of Sinn Fein , she officially takes over on February 10th. Gerry Adams has been the president of the party since 1983 but in 2017, announced he would be resigning from his post.