The US Navy has said an aircraft carrying 11 crew and passengers has crashed into the Pacific Ocean.
According to a statement from the Navy, the names of the crew and passengers who were onboard are being withheld pending the notification of their next of kin.
The C2-A Greyhound aircraft was on a routine flight from Marine Corps Air Station Iwakuni in southern Japan to the USS Ronald Reagan aircraft carrier, which is now in the Philippine Sea on exercises with Japan's Maritime Self-Defense Force.
The cause of the crash was unclear, as was whether any of those aboard the aircraft had survived.
"From the U.S. military, we have received an initial report that engine trouble might be the cause", he said.
In Washington, the White House said President Donald Trump had been briefed on the crash.
"Personnel recovery is underway and their condition will be evaluated by USS Ronald Reagan medical staff", it said. "Prayers for all involved".
NHK says the aircraft was a C2 transport plane.
The Ronald Reagan last week was one of three American aircraft carriers that held rare joint drills in the region, joined separately by Japanese navy and South Korean warships over the weekend.
The cause is under investigation, but Japanese Defense Minister Itsunori Onodera told reporters Wednesday that engine trouble may have been a factor.
It is thought at least three people are missing. The ship was taking part in Annual Exercise 2017 (AE17), a bilateral field-training exercise with the Japanese Navy conducted in waters off Japan from November 16 to November 26.
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